It’s no secret that, as a dietitian, I’m against most dietary supplements. They’re unregulated and typically unnecessary. But still, people ask me all the time: Are supplements worth it? And while my answer is usually ‘no,’ I think it’s important to explain why that is.

Supplements are unregulated.
The supplement world is a black hole of “wellness.” And I mean that in the broadest possible sense. These days, there’s a pill, powder, or tincture for pretty much everything. Don’t like your wrinkles? Chew on a collagen gummy. Feel a little blue? Get yourself some #Mood Pills. Worried that your hormones are “out of balance” (whatever that might mean?). Try an organic superfood latte powder to balance them right back.
No matter what you’re struggling with, there’s a supplement for it. This is an untested hypothesis, but I bet if you Google “[insert LITERALLY ANY physical, mental, social, or emotional woe here] supplement” right now, several relevant results will come up. The options are endless.
Of course, the vast majority of these options are also completely useless. (For an example, check out my review of GEM Vitamins.) Supplements are classified as food products, not pharmaceuticals. That means they’re not tested or regulated the way both prescription and over-the-counter drugs are. All supplements are considered safe until proven otherwise. And supplement manufacturers don’t have much incentive to conduct expensive clinical trials. They’re not necessary for sales or marketing purposes. And, they might prove the product to be unsafe and therefore unsaleable.
Supplement marketing is extremely misleading and intentionally manipulative.

Even if you know how sketchy the supplement industry is, it’s easy to get drawn into their marketing. I get several DMs and emails a week asking me about various supplements. Often, they’re from people who have already done the work of rejecting dieting and the thin ideal, but who still fall for some of the false promises that supplement companies make.
I usually respond with a few sentences on what I think about the supplement (it always starts with, ‘talk to your doctor or dietitian,’ and almost always ends with, ‘there’s no legitimate evidence that this supplement has any benefit.’) But, I’ve realized that while these responses might be helpful in the moment, they don’t really give someone the tools to be able to think critically about the other supplements that they’ll no doubt come across in the future.
Are supplements worth it?
So, to help you figure out for yourself whether or not a supplement is worth your money — although, spoiler: the answer is almost always no — I’m going to walk you through three questions you should ask before you buy. The first two might already be familiar to you, but most people don’t really understand the third, and that’s usually how supplement marketers get you.

1. Did a doctor, dietitian, or primary care provider recommend this supplement?
The supplement industry may have completely lost its marbles in recent years, but before the wellness industry completely infiltrated our lives and our views of health, supplements were mostly used as a way to fix nutrient deficiencies. And for that, they can be great!
But these days, most of us diagnose ourselves as deficient in certain nutrients based on symptoms we’ve read about online. (Getting cramps? Must be a magnesium deficiency! Feeling tired and weak? Iron deficiency!) That’s not scientific at all. And it’s risky for a few reasons.
First, if you feel like there’s something wrong and you take a wild guess at diagnosing the problem yourself, you could be overlooking the actual problem (and letting it go unaddressed).
Second, you run the risk of getting way too much of a certain vitamin, mineral, or other nutrient. In some cases, that’s not a huge problem; in other cases, it can be toxic.
Third, you’re spending money on something you just don’t need.
If you think you’re lacking in a certain nutrient, talk to your primary care provider about it. They might run a blood test to see if that’s actually the case. Sometimes, a dietitian may also be able to suggest supplements based on your diet and what you might be missing (for example, vegans might need B12 supplements).
2. Did a doctor, dietitian, or primary care provider recommend this supplement *based on a lab test that showed a deficiency*?
As a dietitian, I wish I could tell you to wholeheartedly trust every recommendation that your medical care team makes for you. But unfortunately (and especially when it comes to supplements), they may be recommending something to you that isn’t evidence-based or appropriate.
When it comes to nutrition and supplementation, there’s still so much that we don’t know. And that can be frustrating, especially if you’re struggling with uncomfortable symptoms and your medical team can’t figure out (or takes time to figure out) what you can do or take to manage them. In these situations, some healthcare providers might actually recommend supplements that don’t have much evidence behind them. Hopefully, they’ll be honest about the fact that they’re not recommending said supplement because of a proven deficiency, and that supplementation may or may not work. If this is the case, it’s up to you whether to follow their advice or not. And if you do decide to follow it, think critically about how the supplement is OR ISN’T helping or hurting you, and only continue using it if there are noticeable benefits.
3. Does the supplement’s marketing make claims that sound science-y without any actual mention of proven results?
This section is particularly important. Being able to spot (and, most likely, dismiss) mechanistic evidence is probably the best and most efficient way to spot supplement bullshit.
So, what is mechanistic evidence? In the context of supplements (and drugs), mechanistic evidence is evidence based on a certain nutrient or compound’s role in a certain biological pathway. A simpler way to think about it is that mechanistic evidence focuses on the role a certain compound plays in a specific bodily function that’s related to whatever symptom you’re trying to alleviate or health benefit you’re trying to reap. But, it doesn’t provide any proof that said compound actually affects the end result you’re looking for (alleviating the symptom or reaping the benefit). Am I making sense? Maybe not, so here’s an example:
Most supplements that claim to boost your mood, including the #Mood Pills I mentioned above, contain an amino acid called gamma-aminobutyric acid, or GABA. This is because GABA is a neurotransmitter that works in your body by blocking certain brain signals and decreasing the activity in your nervous system. That’s its mechanism. And, supplement companies cite this mechanism when they put GABA in their “mood-boosting” or “stress-reducing” products.
Mechanistic evidence isn’t proof that a supplement works. Not at all!
But, just because GABA is involved in a certain neurological pathway might decrease overall stress, doesn’t mean that taking a GABA supplement actually will decrease stress. Assuming this is making a HUGE leap. It sounds science-y to cite the mechanism, but that doesn’t make the claim evidence-based. In order to actually prove that GABA might reduce stress, researchers would need to conduct clinical trials in which they actually gave people specific doses of GABA and then measured their stress levels. And so far, there’s not much research on this at all, save from a few very small (usually a couple dozen participants), very short (a few weeks) studies.
When you start looking for this kind of inconclusive but scientific-sounding evidence in supplement and diet marketing, you start finding it EVERYWHERE.
In my Whole30 issue a few weeks ago, I mentioned that the diet creators cite all kinds of evidence like this. Specifically, I talked about how they make the claim that grains are bad for health because phytates, a compound in grains, can block absorption of certain nutrients in the body. That (the nutrient absorption) is a mechanism. But, Whole30 twists that to mean that grains are unhealthy and lead to poor nutrition. And that just isn’t the case at all. Large studies (of which there are many) actually show that grain consumption improves health in several ways. Phytates are only a potential problem when a person eats only grains, as in some developing countries, and therefore doesn’t get adequate nutrients from other foods.
The bottom line: Supplement marketers misrepresent science to trick you into buying their product.
It’s kind of a white lie — they highlight something that is true (the mechanism), but conveniently leave out the fact that there’s no proof of any end result.
At the end of the day, no single supplement can cure your health problems. Most likely, it’s your perspective on what health really means that needs to shift. Instead of looking for quick fixes or following trends, think about living in a way that aligns with your values, health-related and otherwise.
If you struggle with an eating disorder, disordered eating, bingeing, dieting, orthorexia, or lots of guilt, shame, and worry about food, a supplement is not the answer. Most likely, it’ll make your problems worse. Instead, working with a registered dietitian can help you break free from unhealthy patterns for good. To learn more about my nutrition counseling services, go here (virtual coaching) or here (in-person counseling in Raleigh, NC). Not ready for 1:1 counseling? Sign up for the Quit Your Diet Newsletter.
You might also like:
What Is Orthorexia — And Do I Have It?
Intuitive Eating 101: What You Need to Know About Set Point Weight
Body Acceptance Is Key to Intuitive Eating. Here’s How to Practice It.
Drucker Labs Intramax is an exceptional liquid multivitamin in my opinion. I would absolutely be THRILLED to hear you trash it !!!
I also believe that as we age, we require ubiquinol (not ubiquinone) and a premium phospholipid complex. I have found Script Essentials to be a trustworthy brand. Taking the DHA Script (with the correct ratio of DHA to EPA) my cholesterol picture (ratio of HDL to LDL) vastly improved — so much so that my doctor ordered a repeat lab. This particular product is no longer available due to sourcing issues.
Generally I agree with your assessment of the supplement industry, with the caveat that I don’t find the FDA to be a trustworthy bunch overall (e.g. 1- the musical chairs starting in the 1990s between GMO advocates in high positions alternating between working at the FDA and Monsanto; 2- the approval process merely requires that the drug manufacturer prove their drug does what it’s supposed to do with little regard for harmful effects {think statins} on the human body as it struggles to detoxify itself from the “constituents” of whatever drug; 3- the wolf is guarding the henhouse {it’s incumbent on the manufacturer to monitor and report dangerous side effects, Vioxx and Oxycontin come to mind as two of the most egregious.)
However I DO believe that most people ARE deficient in even basic nutrients, the result of the “food” industry (1) stripping the nutrients naturally present in the food during their shelf-life focused processing and then “enriching” with synthetic vitamins originating from petroleum, coal tar and the like; (2) an underregulated GRAS list which includes too many substances that are NOT safe (synthetic additives, again shelf-life related); (3) depletion of our soil from over-planting, failure to rotate crops, addition of synthetic fertilizers, etc. A urine organic acids test, such as Genova Labs offers, shows many health issues long before an illness manifests by detecting various problems which all “boil down” to inflammatory markers of one sort or another. This test has been a mainstay of functional medicine practitioners for MANY years and is finally receiving the attention of allopatric medicine. Each lab analysis is accompanied by a list of suspected nutritional deficiencies. My experience with this test is after supplementing with the recommended vitamins and minerals, subsequent tests showed significant improvements in nearly every category. I’ve oversimplified this test for the sake of brevity.
The main problem with standard lab tests that purport to show levels of important nutrients is they are blood tests. Knowing how much b-12 is in one’s blood isn’t particularly helpful; you can be over the limit and still deficient in usable b-12. This is discussed on one of the government’s websites dealing with dietary and nutritional subjects. As I write this I don’t recall the URL or specific department.
Your anti-supplement stance runs afoul of the evidence. It would be far more helpful if you could educate those of us without several letters after our names on how to ascertain our actual nutritional status and then how to analyze supplements to make sure we’re not buying crap. Ninety-nine percent of the supplements sold are worthless or can actually damage our bodies. For instance, the legal definition for vitamin C is ascorbic acid but vitamin C is a complex consisting primarily of ascorbic acid, but not solely. Synthetic vitamin C actually robs the body of natural vitamin C.
All this stuff can be verified on government websites IF you know where to look. It’s hidden.
I realize I went down many rabbit trails here. My original question concerning Drucker Intramax (which has been independently tested by Fenestra Labs but many moons ago) is my main concern but I’d welcome your response to any of the other matters I touched on.
I’m also interested to know where you got your various degrees.
Thank you for your time.
Debra, very well stated. I agree with most of what you are saying and a better knowledge of vitamins in general would be very helpful. After my latest blood work, I also had a few vitamin deficiencies that needed to be supplemented. I’m curious as to the brand you have found to be the best.
I like Nature Made brand! Most of their supplements are verified by the United States Pharmacopoeia (USP), a trusted third-party laboratory, so you can trust that you’re getting what’s on the label. They’re also inexpensive and available at most pharmacies and supermarkets.